Wednesday, October 26, 2011

MoNews 10/26/11

Prostate Cancer Growth Slowed by Fish Oil Supplements
- The rate at which prostate cancer grows can be slowed by a low-fat diet and fish oil supplements, research suggests.
- U.S. researchers made the discovery after testing prostate tissue samples taken from men with the disease. They found that just four to six weeks on the diet was enough to reduce the growth of cancer cells. The same effect was not seen in men who remained on a regular diet with no fish oil supplements.
- “The lower the rate of proliferation, the lesser the chances that the cancer will spread outside the prostate, where it is much harder to treat.”
- The low-fat diet relied on fat to provide just 15 percent of calories. Men on the diet also took five grams of fish oil per day in five capsules.
- “Preclinical studies suggest that lowering dietary omega-6 fatty acids from corn oil and increasing omega-3 fatty acids from fish oil decreases the risk of prostate cancer development and progression,” the scientists wrote in the journal Cancer Prevention Research.
 

Monday, October 24, 2011

MoNews 10/24/11

U.S. panel wrong to discount prostate cancer test
SUMMARY - When I hear or see bad medical advice being given, I simply cannot remain silent. Such is the case with the recent U.S. Preventive Services Task Force (USPSTF) recommendation that healthy men no longer need to receive PSA (prostate-specific antigen) blood tests as part of routine cancer screening.
CONCLUSION - Medical decisions should be made by a patient and his physicians. I honestly thought we had moved past the point where we would permit the government to deny patients’ ability and right to choose their own health care destiny.
 

Tuesday, September 6, 2011

MoNews 9/6/11

Prostate cancer can be beaten
- September is Prostate Cancer Awareness Month, and this campaign serves as an important reminder to be aware of what is truly a "silent disease" growing.
- Prostate cancer, the most common form of cancer in the United States, also is the second leading cause of cancer deaths in men.
- This cancer can develop without obvious symptoms, hence the "silent killer" label, but it definitely doesn't have to be.
- Early detection is so important in slowing down the disease.
- Statistics from the National Prostate Cancer Coalition show approximately 317,000 men will be diagnosed with prostate cancer this year, and approximately 41,000 will die as a result of the disease.
- Men should know that nearly 100 percent of those diagnosed with prostate cancer are still alive in five years.
- That is why doctors recommend men over the age of 40 make an appointment to receive a yearly exam.
- Men who are at high risk, especially African-Americans or those who have family members with prostate cancer, should begin testing earlier.
- Since the use of early detection tests for prostate cancer became relatively common about 20 years ago, the death rate has dropped, according to American Cancer Society reports.
- New research also shows a low-calorie diet may help reduce prostate cancer risk, and doctors now recommend eating a balanced diet, exercising daily and limiting alcohol consumption.
 
Warnex Launches New Website: pca3.ca
- Warnex Inc. announced today the launch of its new website www.pca3.ca for its PCA3 test for prostate cancer detection, available throughout Canada.
- Warnex's PCA3 test is a simple, non invasive test performed on a urine sample that informs a patient on their risk of having prostate cancer.
- "The Warnex PCA3 test for the detection of prostate cancer is highly specific and more precise than all other available screening tests for prostate cancer," said Mark Busgang, President and CEO of Warnex.
- Offered since 2008, Warnex's PCA3 testing service uses advanced PCR technology to detect mRNA from the prostate cancer gene 3 (PCA3).
- Warnex uses a molecular biology assay to measure the expression of PCA3 mRNA in urine samples.
- PCA3 is specific to the prostate and is significantly up-regulated (60-100 fold) in prostate cancer.
- The test quantitatively measures PCA3 mRNA as well as PSA mRNA and determines their ratio.
- High ratios have been shown to be indicative of prostate cancer.
- PCA3 screening may help to reduce the number of unnecessary biopsies.
- Prostate cancer usually grows slowly and can often be cured or managed successfully.
 
September is Prostate Cancer Month
- While most of us would like to be content in our own little cocoon and believe that cancer is something that happens to someone else, the reality is far from that. Generally speaking, most men will do anything to avoid a visit to a physician. They have to be in a lot of pain before they will make an appointment.
- Prostate cancer is the second leading killer (behind lung cancer) among men in the USA. Early detection and treatment are key factors in addressing prostate cancer. The sentence you just read is so very important that I encourage you to read it again.
- "Early detection and treatment are key factors in addressing prostate cancer."
- No one knows the exact cause of prostate cancer.
- Age is the strongest risk factor for prostate cancer.
- The disease is rare in men younger than 45, but the chance of getting it goes up sharply as a man ages.
- A man’s risk of prostate cancer is higher than average if his brother or father had the disease.
- There simply is no excuse for men to not get a yearly prostate cancer screening test.
- Most group and individual health insurance plans have a "routine" benefit that is now unlimited. It must be coded as preventive. This can include a routine physical, a mammogram, a prostate cancer screening and even a flu shot.
 

Friday, September 2, 2011

MoNews 9/2/11

Prostate Cancer Awareness Month Starts in September
- What do Robert DeNiro, Hugo Chavez, Rudy Giuliani, Roger Moore, John Kerry, Don Imus, Harry Belafonte, Nelson Mandela, Colin Powell, Frank Zappa, Telly Savalas, Bill Bixby and Timothy Leary all have in common?
- If your answer is prostate cancer, then you would be correct.
- DeNiro, Giuliani, Kerry, Imus, Belafonte, Mandela and Powell were all diagnosed and successfully treated. Chavez, the President of Venezuela, is in treatment and battling the disease. Unfortunately, prostate cancer claimed the lives of Zappa, Savalas, Bixby and Leary.
- About 217,730 new cases of prostate cancer will be diagnosed this year and some 32,000 men die of prostate cancer--the second leading cause of cancer death in American men, behind only lung cancer.
- Through Dr. Bert Vorstman's new Prostate Cancer Advocacy Help Center and his website, www.hifurx.com , patients and their spouses can access a broad spectrum of information relevant to localized prostate cancer.
- Dr. Vorstman's call to action is simple:
*Promote Early Diagnosis
*Promote Regular Testing
*Empower Patients to Fully Understand Their Condition and Treatment Options
 

Thursday, September 1, 2011

MoNews 8/1/11

New test for prostate cancer works independently of PSA concentration
- A new, urine-based screening test known as the PSA/SIA assay may be more sensitive than traditional methods in detecting prostate cancer.
- the prostate-specific antigen/solvent interaction analysis (PSA/SIA) test is described as a novel prostate cancer assay that focuses on changes to the structure of PSA.
- “This test provides a new way to look at prostate cancer diagnosis utilizing a novel biological assay which differentiates PSA molecular structures arising from cancer versus noncancerous glands,” affirmed Mark Stovsky, MD, principal investigator and lead author of the study.
- the accuracy of traditional PSA testing is limited by both relatively high false-positive rates of approximately 55% to 75% and false-negative rates of up to 15%. False positives lead to unnecessary biopsies and worry on the part of patients, whereas false negatives cause clinicians to miss cancer in men with “normal” PSA values.
- Rather than attempting to find a single genetic biomarker (PSA) that predicts the presence of prostate cancer, the PSA/SIA assay works by separating PSA protein structures on the basis of being linked to either a “cancer” or a “noncancer” pathologic diagnosis based on ultrasound-guided biopsy.
- “In this preliminary study, analysis of the overall structurally heterogenous PSA isoform population using the SIA assay showed promising results to be further evaluated in future studies,” concluded the investigators.
 
 

Wednesday, August 31, 2011

MoNews 8/31/11

Experts recommend PSA testing during prostate cancer awareness month
- Prostate cancer awareness month (September) is just a few days away, and experts are urging men to seek PSA testing if they have any of the common risk factors for the condition, which include age.
 

Tuesday, August 30, 2011

MoNews 8/30/11

Blue Bulb Brigades Fight Prostate Cancer With Light
- Prostate cancer survivors have enlisted men across America into Blue Bulb Brigades, telling each other to get a blue bulb and light it on their porch, on their front windows, over their driveways, where ever their neighbors can see it, starting conversations about early detection and treatment.
- Men are lighting blue bulbs every night this September, Prostate Cancer Awareness month, to provoke conversations with their neighbors about early detection and treatment.
- “The Blue Bulb Brigade gives each guy a chance to show off his fighting spirit. And that spirit translates into lifesaving healthcare choices, including self advocacy,” said Mr. Mitteldorf.
 

Wednesday, August 24, 2011

MoNews 8/24/12

New Website For Prostate Cancer Information
- The Prostate Cancer Foundation today announced its launch of a mobile website that enables individuals to easily access information on prostate cancer and stay informed on the latest research news.
- Any smartphone device can access the Prostate Cancer Foundation mobile website by visiting: http://www.pcf.org
- "With the addition of a mobile website, prostate cancer patients, caregivers and supporters have convenient access PCF's extensive data on disease and treatment information," says Dan Zenka, Sr VP of Communications at PCF.
 

Wednesday, August 3, 2011

MoNews 8/3/11

Can Drinking Coffee Help Prevent Prostate Cancer?
- A new study from the Harvard School of Public Health that lasted 22 years says that men who regularly drink coffee—even one to three cups a day--appear to have a lower risk of developing a deadly form of prostate cancer. And it doesn’t matter if it’s regular or decaf coffee.
- Coffee was chosen for this study because the drink has a number of “beneficial compounds” that act as antioxidants, reduce inflammation, and regulate insulin, all of which may influence prostate cancer.
- Caffeine and phenolic acids in coffee have potent antioxidant activity which can affect glucose metabolism and sex hormone levels.
The Harvard study followed nearly 48,000 men who reported their coffee consumption every four years from 1986 to 2008.
The researchers concluded:
- Men who drank the most coffee (six or more cups daily) had nearly a 20% lower risk of developing any form of prostate cancer.
- Men who drank the most coffee had a 60% lower risk of developing prostate cancer that leads to death or spreads to the bones.
- The lowered risk does not seem to be related to caffeine, because the men drank decaffeinated or regular coffee.
- Even drinking one to three cups of coffee per day was associated with a 30% lower risk of lethal prostate cancer.
 
No one is prepared to conclusively link coffee with reduced risk for prostate concern, but the Harvard researchers said, “We observed a strong inverse association between coffee consumption and risk of lethal prostate cancer. The association appears to be related to non-caffeine components of coffee.”
 

Monday, August 1, 2011

MoNews 8/1/11

Young Triathlete Raises Awareness, Money For Prostate Cancer Foundation
This is inspiring and if you follow the link, there is a nice 1:30 video that is impressive.
- Winter Vinecki is the 2010 IronKids National Champion and the 2011 IronKids Ambassador.
- At just 12-years-old she is winning medals, while at the same time trying to save lives.
- Winter founded "Team Winter" at age nine after doctors diagnosed her dad, Michael, with an aggressive form of Prostate Cancer.
- He passed away ten months later.
- Since starting "Team Winter," Winter has helped raise close to $300,000 for prostate cancer research.
- There are currently more than 200 athletes from around the world racing for "Team Winter."
- Because the family doesn't spend much time in Gaylord anymore, they are planning to turn their home into a retreat for prostate cancer survivors.
 
 

Friday, July 15, 2011

MoNews 7/15/11

Tomatoes help prevent prostate cancer
- Lycopene, a red pigment that gives tomatoes their distinctive colour, could help prevent prostate cancer, say scientists.
- Lycopene is a potent antioxidant and some studies have shown that tomato-rich diets may lower the risk of certain cancers, especially those of the prostate, lung and stomach.
- Men who received lycopene showed "a significant increase" of the antioxidant in the blood, van Breemen said, compared to the placebo control group.
 

Thursday, July 14, 2011

MoNews 7/14/11

DNA Regions That Influence Prostate Cancer Risk Identified
- Scientists have discovered the exact DNA variants that contribute to prostate cancer risk.
- In a multi-stage study, the collaborators systematically searched the whole genome of cancer patients and healthy controls for specific gene variants. Then they calculated whether specific variants are found more often in patients than in healthy people.
- Professor Dr. Hermann Brenner, explains: "Each of these gene variants taken on its own is associated with only a slight increase in prostate cancer risk by a few percent. However, by taking account of the different variants at the same time it becomes possible to identify groups of persons who have a significantly elevated risk. Examining the genetic material for such risk variants might therefore improve medical consultation on the prevention and early detection of prostate cancer in the future." 
- Such DNA variants are scientifically called single nucleotide polymorphisms (SNPs).
- Alongside a number of already identified variants, the investigators found seven SNPs that emerged for the first time in association with an elevation in prostate cancer risk. The variants are all located in DNA regions that also contain genes for which the scientists consider it plausible that they play a role in carcinogenesis. 
- With the seven newly discovered DNA regions, scientists are now able to explain about 25 percent of familial cancer risk.

Wednesday, June 29, 2011

MoNews 6/28/11

PCA3 May Help Predict Insignificant Prostate Cancer
- Prostate cancer gene 3 (PCA3) may be a valuable predictor of pathologically confirmed low volume disease and insignificant prostate cancer (PCa)
- PCA3 urine test may be a good predictor of low-volume disease and may have a future role in managing patients on active surveillance protocols.
- “When you shed PCA3 cells in the urine you can get a PCA3 score and that means if you have a cancer in your prostate you will have a higher quantity of PCA3”
- “If what is sloughed off in the urine is reflective of what is happening in the prostate it would have tremendous application in not just in detecting cancer but also in monitoring patients who are now subjected to serial biopsies”
- The PCA3 test is approved in Europe and its approval is being considered by the FDA.
 

Friday, June 24, 2011

MoNews 6/24/11

Prostate Cancer Treatment Study: Immunotherapy Drug Treatments for Prostate Cancer - Progress and Setbacks - SMART Surgery
- researchers have dreamed of curing prostate cancer with targeted drugs
- Recent approvals of immuno-modulatory drugs Provenge and Yervoy represent considerable progress in this domain, as they have already been shown to improve survival rates in certain types of metastatic prostate cancer
- "There is no doubt that these drugs represent a great scientific accomplishment. However, they do not eradicate all of the cancer cells in the body. They do delay prostate cancer recurrence but, eventually, the disease can become resistant to their effects."
- In contrast to these new drugs, robotic prostatectomy has been shown to provide one of the highest prostate cure rates of any primary treatment.
- Using SMART Surgery (Samadi Modified Advanced Robotic Technique), Dr. Samadi is able to preserve the delicate nerve bundles responsible for urinary control and sexual function. This technique not only cures cancer in 97% of his patients, but also preserves sexual and urinary function among 85% and 96% of his patients, respectively.
- "While the new drugs can put up a good fight against prostate cancer, there's only one way to win the war against this disease, and that's surgery"
 

Wednesday, June 22, 2011

MoNews 6/22/11

Men can recover from side effects of prostate treatment, experts say
This is EXACTLY what happened to my father-in-law.  He ignored his elevated PSA score because he was getting re-married, and he didn't want to face the possibility of having any problems with his sex-life.  As a result, he never went back to the doctor to follow up, until he was doubled-over in pain one day, about 2 years later.  Then it was too late, and he was told that he had inoperable prostate cancer and that he probably had 3 years to live.
- Following a positive PSA test for prostate cancer, men have many concerns. Chief among these is often the worry that they won’t be able to enjoy a satisfying sex life after they have surgery or radiation therapy to treat the condition. However, experts say that this is frequently not the case.
- men often confuse psychological conditions with physical hindrances following surgery. However, talking through these issues may help them regain a normal sex life.
- "On average, 8 out of 10 men I see who have had prostate surgery continue having sex lives afterwards”
- fear of sexual and other side effects is one of the main reasons men give for not seeking prostate treatment early, but experts say this is no excuse for not seeking PSA testing.
 

Tuesday, June 21, 2011

MoNews 6/21/11

 
Prostate cancer cured in mice: Are humans next?
This is an excellent follow up article from yesterday's news.
There is still a lot of work to do, but this is clearly exciting news!
- (CBS) There's still no cure for prostate cancer, but scientists may be closing in on one. They say they've developed a vaccine that destroys even advanced prostate tumors without any side effects.
- By using DNA from healthy prostate cells, the researchers created a vaccine that tricks the immune system to think existing tumors are antigens - like an invading flu virus, for example - thus triggering its antibodies to destroy the tumors.
- In mice, 80 percent of prostate cancer cells were destroyed without harming healthy tissue, the Daily Mail reported.
- How far off is a human version of the vaccine cure? Study author Dr. Richard Vile, professor of immunology at the Mayo Clinic, told HealthDay it might take "three to five years." He said more research was needed to clear some FDA hurdles.
 
Smokers face higher prostate cancer risk
- Smokers who are diagnosed with prostate cancer are more likely to have aggressive tumors and face a higher death risk from the disease than non-smokers.
- Men who smoked at the time of diagnosis faced 61 percent higher risk of dying from prostate cancer and a 61 percent higher chance that the cancer would come back compared to men who never smoked, said researchers at the Harvard School of Public Health and University of California, San Francisco.
- “For smokers, quitting can impact their risk of dying from prostate cancer. This is another reason to not smoke.”
 
 

Monday, June 20, 2011

MoBlog 6/20/11

Human Vaccine Cures Prostate Cancer in Mice
- Amazing potential... Reported by Popular Science magazine...
- By injecting snippets of complementary DNA from a healthy prostate into viruses, and in turn injecting the viruses into mice with prostate cancer, Mayo Clinic researchers have coaxed the mice's immune systems into eradicating the cancer. CDC
- Mayo Clinic researchers and collaborators from the UK have apparently cured mice with well-established prostate tumors with no visible side effects via a new kind of tumor vaccine
- The findings are preliminary but promising. Geneticists basically assembled a complementary DNA library from healthy prostate tissue and inserted snippets of that genetic code into a swarm of viruses that were introduced to the mice intravenously. This cDNA causes the viruses to produce prostate antigens, basically sending the immune system a distress signal with the prostate’s unique signature on it.
- That’s big news for men, and could be big news for anyone affected by a variety of cancers, including lung, pancreatic, and even brain cancers
 
Virus-Expressed Normal Human cDNA Library Cures Prostate Cancer in Mice
- Same news but reported in Genetic Engineering & Biotechnology News.
- Researchers have developed a virus-based vaccine expressing a broad spectrum of undefined antigens from normal human prostate tissue that they claim completely eradicates established mouse prostate tumors in experimental animals.
- This is a much more technical and detailed report of the findings as reported in Nature Medicine.
 
House to cut prostate drug research
- ZERO, The Project to End Prostate Cancer, says the House Appropriations Committee approved a bill that would reduce by 20 percent the Prostate Cancer Research Program, part of the Department of Defense's Congressionally Directed Medical Research Program for fiscal year 2012.
- Since 2006, funding for the program had been $80 million a year to develop new drugs, but for next year the funding would drop to $64 million, Lockwood says.
 

Friday, June 17, 2011

MoNews 6/17/11

New hope with prostate cancer treatment - Provenge
- This is a very good 3-minute video about Provenge, a new immuno therapy treatment.
- Provenge is a custom made vaccine made from the patient's blood.
- White blood cells are pulled from the patient's bloodand then sent to the makers of the vaccine, where prostate specific proteins are added to cells in order to train them to fight the cancer cells.
- Three days later that vaccine is slowly infused back into the patient.
- This process is repeated every two weeks for a total of three treaments.
- Initial studies found that provenge increased survival by about 4 months.
- There are studies underway to see if it can one day be a method of prevention / a vaccine against prostate cancer.
- At $93,000 the treatment is expensive.

Wednesday, June 15, 2011

MoNews 6/15/11

Prostate cancer more lethal than previously thought
- Half of men with prostate cancer die from the disease itself, according to a new study published today, exploding the myth that it is usually not fatal.
- the old notion that 'most men die with it, not of it' is simply not true for men with advanced prostate cancer.
* This is an interesting article because it could impact how to treat PC once it is discovered, even in advanced cases.
 
Next-step da Vinci: Prostate, kidneys & beyond
- This is an excellent video and report that shows how "Da Vinci' robotic surgery is done on 90% of prostate procedures
- AND now it is being used for kidney operations and soon for kidney cancer.
- "Armed with cutting edge technology, surgeons can offer their patients less invasive options.
Putting them back on their feet in less time with less complications."
 
Toe fungus drug appears to tame prostate cancer
- 'A clinical trial at Johns Hopkins University suggests the oral antifungal medication itraconazole can slow the progress of advanced prostate cancer and delay the need for chemotherapy.'
- But... 'more research is needed because the drug has the potential to contribute to congestive heart failure and produce other side effects.'

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Monday, June 13, 2011

MoNews 6/13/11

Get involved ->www.Movember.com -> Grow your Mo, Save a Bro!
Thank you to our Movember Team Sponsor -> Rip Curl USAwww.RipCurl.com
 
In The MoNews Today -
 
"Prostate Cancer --- To Screen or Not To Screen?"
 
This is an excellent article from the Huffington Post that provides:
- A very good 4:26video from TheVisualMD that the article is based off of.
- An overview of what the prostate is, and some statistics that define the scope prostate cancer (PC)
- The challenges of diagnosing PC.
- Arguments FOR screening for PC.
- Arguments AGAINST screening for PC.
- Understanding your risk factors of getting PC.
- Strategies for reducing the risk of getting PC.
 
This is one of the better articles that I have read as itprovides a broad overview of the issues, and the video is a great visual that everyone interested should watch.
 
"Lessons from a full-time dad"
This is a touching and nice article from the Chicago Tribune.
- When Jim Higley was diagnosed with prostate cancer, it made him stop and savor his life.
- He used to work long hours in commercial real estate to provide money in the bank, but it gave him little connection with his kids. 
- Being diagnosed and treated for PC inspired him to quit his job in order to be a full-time dad and to write a book called "Bobblehead Dad: 25 Life Leffons I Forgot I Knew"
(Greenleaf Book Group Press, $14.95)
 
Here are the Bobblehad Dad's top 5 life lessons:
- Celebrate something every day  
- When you can't be brilliant with words, be brilliant with your arms
- Expect the unexpected
- There's only one person stopping you from who you were meant to be.
- Lessons happen every day - that's why we need to live in the moment.
 
"Men care more about cars than their health because of 'big boys don't cry' syndrome, new survey shows" ->From MailOnline
- "Nearly 70% of men find it easier to care for their cars than they do their personal health"
- Men are taught from a young age to 'tough it out' and this mindset contributes to why men are dismissive about signs of trouble.
- 'At age 40, the body begins to change and men are past the maintenance-free years.'
- The moral of the story, and this article is.... get checked regularly, and don't ignore any signs of treatable health conditions!

Sunday, June 12, 2011

Welcome

Welcome to my MoMoJo blog!

I like to read the NEWS about PROSTATE cancer, because it is all MOving so fast.
Because I have been so involved with prostate cancer and men's health issues in general, I get a lot of questions from friends about the topic, so I try to keep up on the topic, and I thought it might be cool / helpful to try to capture and summarize some of the flow of news here.

I am by no means a doctor, or even a researcher, I'm just a guy who's family has been touched by prostate cancer.  This cancer that can be almost 100% avoided if detected early, so be aware, and get checked regularly.

I hope this is helpful, and I hope you will enjoy keeping informed too.

~ Sandy Goodman

Here is an excellent way to get involved -> www.Movember.com